D-Mannose is a simple sugar that occurs naturally in some plants, including cranberries. Although small amounts of D-Mannose are metabolized by the human body, much of it is rapidly excreted in the urine. In the bladder, D-Mannose may adhere to undesirable foreign substances, preventing them from sticking to the lining of the bladder. Our NOW natural and organic Supplements are an effective way to ensure you and your loved ones are getting essential vitamins, minerals and nutrients for daily optimal health. Since 1968, NOW has been making top quality products that are tested to the highest standards to empower people to lead healthier lives. Our promise - what is on the label, is precisely what is in the bottle.